Real-time optimization of right to left ventricular timing...

Details Real-time optimization of right to left ventricular timing... Real-time optimization of right to left ventricular timing...

A - Human Necessities

61

N

A61N 1/362 (2006.01) A61B 5/103 (2006.01) A61N 1/365 (2006.01)

Patent

CA 2559254

A system and automated method for assessing ventricular synchrony in ambulatory patients is provided including at least one mechanical sensor (e.g., accelerometer, tensiometric sensor, force transducer, and the like) operatively coupled to a first myocardial location in order to measure a wall motion signal of a first chamber, and a second mechanical sensor operatively coupled to a second myocardial location in order to measure a wall motion signal of a second chamber. The wall motion signals are processed in order to identify the time at which a fiducial (e.g., an inflection point, a threshold crossing, a maximum amplitude, etc.) occurs for each respective signal. The temporal separation between the fiducial points on each respective signal is measured as a metric of ventricular synchrony and can be optionally utilized to adjust pacing therapy timing to improve synchrony.

L'invention concerne un système et un procédé automatisé permettant d'évaluer la synchronie ventriculaire chez des patients ambulatoires, lequel système comprend au moins un capteur mécanique (p.ex., un accéléromètre, un capteur tensiométrique, un transducteur de force, et analogue) fonctionnellement couplé à un premier emplacement myocardique afin de mesurer un signal de mouvement de paroi d'une première chambre, et un second capteur mécanique fonctionnellement couplé à un second emplacement myocardique afin de mesurer un signal de mouvement de paroi d'une seconde chambre. On traite les signaux de mouvement de paroi afin d'identifier le moment où un repère (p.ex., un point d'inflexion, un franchissement de seuil, une amplitude maximale, etc.) se produit pour chaque signal respectif. On mesure la séparation temporelle entre les points de repère de chaque signal respectif sous forme de métrique de la synchronie ventriculaire, que l'on peut facultativement utiliser pour ajuster la synchronisation de la thérapie de stimulation afin d'améliorer la synchronie.

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