Rebeccamycin analogs

Details Rebeccamycin analogs Rebeccamycin analogs

C - Chemistry, Metallurgy

07

H

167/202, 260/229

C07H 19/23 (2006.01) A61K 31/70 (2006.01) C07H 19/044 (2006.01)

Patent

CA 1287349

ABSTRACT There are disclosed analogs of the antitumor agent, rebeccamycin, which possess antineoplastic properties against mammalian, particularly experimental animal, tumor systems. The compounds of the invention are aminoalkylated derivatives of rebeccamycin produced by first reacting rebeccamycin with a strong base to obtain a reactive intermediate and then reacting the reactive intermediate with an aminoalkyl compound.

552337

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