Rebeccamycin analogs by tryptophan analogs feeding

C - Chemistry – Metallurgy – 12 – P

Patent

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167/202, 260/229

C12P 19/28 (2006.01) C07D 487/12 (2006.01) C07H 19/04 (2006.01) C07H 19/044 (2006.01)

Patent

CA 2037783

Addition of certain tryptophan analogs to the culture medium during fermentation of a rebeccamycin-producing strain of Saccharothrix aerocolonigenes results in production of new rebeccamycin analogs having advantageous antitumor properties.

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