Receptor for oncostatin m

Details Receptor for oncostatin m Receptor for oncostatin m

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/18 (2006.01) A61K 38/19 (2006.01) C07K 14/705 (2006.01) C07K 14/715 (2006.01) C07K 16/28 (2006.01) C07K 19/00 (2006.01) C12N 15/19 (2006.01)

Patent

CA 2190371

A novel polypeptide functions as the .beta. chain of an oncostatin M receptor and is thus designated OSM-R.beta.. Heterodimeric receptor proteins comprising OSM-R.beta. and gp130 bind oncostatin M and find use in inhibiting biological activities mediated by oncostatin M.

Un nouveau polypeptide fonctionne comme la chaîne .beta. d'un récepteur de l'oncostatine M et est ainsi appelé OSM-R.beta.. Des protéines réceptrices hétérodimères comprenant OSM-R.beta. et gp130 fixent l'oncostatine M et s'utilisent pour inhiber des activités biologiques régulées par l'oncostatine M.

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