Receptor for underivatized, aqueous soluble .beta.(1-3)-glucan

Details Receptor for underivatized, aqueous soluble .beta.(1-3)-glucan Receptor for underivatized, aqueous soluble .beta.(1-3)-glucan

A - Human Necessities

61

K

A61K 31/715 (2006.01) A61K 47/48 (2006.01) C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/566 (2006.01) G01N 33/569 (2006.01) G01N 33/92 (2006.01)

Patent

CA 2253257

A preparation containing a receptor for underivatized aqueous soluble .beta.(1- 3)-glucan is disclosed, along with characterization of the receptor for underivatized, aqueous soluble .beta.(1-3)-glucan. Also described are assays for identifying agents which alter the effect or underivatized, aqueous soluble .beta.(1-3)-glucan on activation of signal transduction pathways and agents identified thereby, as well as assays for assessing the specificity of carbohydrate: glycolipid interactions.

Cette invention concerne une préparation contenant un récepteur de beta (1-3)-glucane non dérivé, soluble dans l'eau ainsi que la caractérisation du récepteur de beta (1-3)-glucane non dérivé, soluble dans l'eau. On décrit également des dosages permettant d'identifier des agents qui altèrent l'effet de beta (1-3)-glucane non dérivé, soluble dans l'eau lorsque les voies de transduction du signal sont activées, et des agents identifiés de cette manière ainsi que des dosages permettant d'évaluer la spécificité des interactions glucide/glycolipide.

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