Receptor specific transepithelial transport of immunogens

Details Receptor specific transepithelial transport of immunogens Receptor specific transepithelial transport of immunogens

A - Human Necessities

61

K

A61K 39/385 (2006.01)

Patent

CA 2210656

Methods and products for modulating am immune response are provided. Pharmaceutical preparations contain a conjugate of an antigen and an FcRn binding partner. The conjugates are administered to mammals in effective amounts to modulate the immune system by stimulating the immune response against the antigen or tolerizing the immune system to the antigen. The antigen may be characteristic of a pathogen, of an autoimmune disease, of an allergen or of a tumor.

Voici des méthodes et des produits servant à moduler une réaction immunitaire. Les préparations pharmaceutiques contiennent le conjugué d'un antigène et d'un agent liant FcRn. Les conjugués sont administrés à des mammifères en quantités efficaces afin de moduler le système immunitaire par la stimulation de la réaction immunitaire contre l'antigène ou par l'augmentation de la tolérance du système immunitaire à l'antigène. Ce dernier peut être caractéristique d'un agent pathogène, d'une maladie auto-immune, d'un allergène, ou d'une tumeur.

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