Receptor, the use thereof, and mouse antibodies

Details Receptor, the use thereof, and mouse antibodies Receptor, the use thereof, and mouse antibodies

C - Chemistry, Metallurgy

07

K

C07K 14/705 (2006.01) A61K 38/16 (2006.01) C07K 16/28 (2006.01) C07K 16/30 (2006.01)

Patent

CA 2455154

The invention relates to a receptor located on the surface membrane of highly proliferative cells, particularly of the gastric carcinoma, which is composed of glycoproteins. At least one determinant of the glycoprotein corresponds with one of the CFR-1 protein, and the human antibody 103/51 and/or the murine antibody 58/47-69 (lgM) specifically binds to the glycoprotein.

La présente invention concerne un récepteur se trouvant sur la membrane de surface de cellules hautement proliférantes, notamment du carcinome gastrique, qui est composé de glycoprotéines, au moins un déterminant de la glycoprotéine correspondant à une protéines CFR-1, et l'anticorps humain 103/51 et/ou l'anticorps de souris 58/47-69 (lgM) se liant spécifiquement à la glycoprotéine.

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