Receptor tyrosine kinase, ar-1, is a regulator of angiogenesis

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/54 (2006.01) A61K 38/45 (2006.01) A61K 39/395 (2006.01) C07K 14/515 (2006.01) C07K 16/40 (2006.01) C07K 19/00 (2006.01) C12N 9/12 (2006.01) C12N 15/62 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2313804

The present invention provides for an isolated nucleic acid molecule encoding human AR-1. The invention further provides isolated AR-1 protein substantially free of other proteins. The invention further provides a host-vector system for the production of human AR-1 and a method of producing human AR-1. The invention also provides an antibody which specifically binds human AR-1 and a composition comprising human AR-1.

Cette invention se rapporte à une molécule d'acide nucléique isolée codant le régulateur d'angiogenèse AR-1 humain. Cette invention se rapporte également à une protéine d'AR-1 isolée, pour ainsi dire exempte d'autres protéines, à un système hôte-vecteur servant à la production de l'AR-1 humain et à un procédé de production de l'AR-1 humain, ainsi qu'à un anticorps qui se fixe spécifiquement à l'AR-1 humain et à une composition contenant l'AR-1 humain.

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