C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/114, 195/129
C12N 15/53 (2006.01) C12N 9/04 (2006.01) C12P 7/60 (2006.01)
Patent
CA 1341085
The invention relates to purification of and recombinant production of 2.5-diketogluconic acid (2.5-DKG) reductase and the use of the reductase so produced in converting 2.5-DKG stereoselectively into 2-keto-L-gluconic acid (2 KLG), as well as to the production of a single recombinant organism capable of synthesizing 2-KLG. The 2-KLG produced is a useful intermediate in the production of ascorbic acid (vitamin C).
590942
Estell David Aaron
Lazarus Robert Alan
Light David Richard
Miller Jefffrey Veach
Rastetter William Harry
Dennison Associates
Genentech Inc.
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