A - Human Necessities – 01 – N
Patent
A - Human Necessities
01
N
A01N 63/00 (2006.01) A01N 43/04 (2006.01) C07H 21/02 (2006.01) C07H 21/04 (2006.01) C12N 15/00 (2006.01) C12N 15/09 (2006.01) C12N 15/63 (2006.01) C12N 15/70 (2006.01) C12N 15/74 (2006.01) C12N 15/864 (2006.01)
Patent
CA 2367648
Disclosed are methods for the use of recombinant adeno-associated virus compositions. In particular, the use of catalase- or superoxide dismutase- expressing rAAV constructs in compositions for delivery to the optic nerve is disclosed. Also disclosed are methods for the treatment and amelioration of symptoms of demyelinating disorders of an animal, such as multiple sclerosis, allergic encephaloneuritis and optic neuritis.
L'invention concerne des procédés d'utilisation de compositions de virus adéno-associés recombinés. Elle concerne en particulier l'utilisation de produits géniques de rAAV exprimant la superoxide dismutase ou la superoxide catalase dans des compositions, en vue d'une administration au nerf optique. L'invention concerne également des méthodes visant à traiter et à améliorer des symptômes d'affections démyélinisantes chez un animal, telles que la sclérose en plaque, l'encéphalonévrite allergique et la névrite optique.
Guy John
Hauswirth William W.
Qi Xiaoping
Guy John
Hauswirth William W.
Kirby Eades Gale Baker
Qi Xiaoping
LandOfFree
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