Recombinant adenovirus coding for glial-derived neurotrophic...

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A61K 48/00 (2006.01) A61K 35/12 (2006.01) A61K 35/76 (2006.01) C07K 14/475 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/18 (2006.01) C12N 15/86 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2184841

Recombinant adenoviruses comprising a heterologous DNA sequence coding for glial-derived neurotrophic factor (GDNF), preparation thereof, and use thereof for treating and/or preventing degenerative neurological diseases.

La présente invention concerne des adénovirus recombinants comportant une séquence d'ADN hétérologue codant pour le facteur neurotrophique dérivé des Cellules Gliales (GDNF), leur préparation, et leur utilisation pour le traitement et/ou la prévention des maladies neurodégénératives.

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