Recombinant adenoviruses coding for acidic fibroblast growth...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 35/12 (2006.01) A61K 38/18 (2006.01) A61K 48/00 (2006.01) C07K 14/50 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12N 15/18 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2184409

Recombinant adenoviruses comprising a heterologous DNA sequence coding for acidic fibroblast growth factor (aFGF), preparation thereof, and use thereof for treating and/or preventing degenerative neurological diseases.

La présente invention concerne des adénovirus recombinants comportant une séquence d ADN hétérologue codant pour le facteur de croissance des fibroblastes acides (aFGF), leur préparation, et leur utilisation pour le traitement et/ou la prévention des maladies neurodégénératives.

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