Recombinant adenoviruses for gene therapy in cancers

Details Recombinant adenoviruses for gene therapy in cancers Recombinant adenoviruses for gene therapy in cancers

C - Chemistry, Metallurgy

12

N

C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 38/45 (2006.01) A61K 48/00 (2006.01) C12N 7/01 (2006.01) C12N 15/85 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2176585

The invention concerns recombinant viruses comprising a heterologous DNA sequence under the control of expression signals specifically active in tumour cells, and their preparation and use in the treatment and prevention of cancers.

La présente invention concerne des adénovirus recombinants comportant une séquence d'ADN hétérologue sous le contrôle de signaux d'expression actifs spécifiquement dans les cellules tumorales, leur préparation, et leur utilisation pour le traitement et/ou la prévention des cancers.

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