C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) A61K 31/7088 (2006.01) A61K 39/395 (2006.01) A61K 48/00 (2006.01) A61P 33/06 (2006.01) C07K 16/20 (2006.01) C12N 15/10 (2006.01) C12P 21/08 (2006.01) C12Q 1/70 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01) G01N 33/577 (2006.01)
Patent
CA 2458890
The present invention relates to a recombinant human antibody comprising an antibodysequence specific for the MSP-3 antigen ofPlasmodium falciparum. In particular, theinvention relates to a recombinant human antibody which is specific for the MSP-3194-257 antigen. The invention further relates to nucleic acid encoding suchantibodies and to uses of these antibodies, in particular in the treatment or prophylaxisof malaria.
L'invention concerne un anticoprs humain de recombinaison comprenant une séquence d'anticorps spécifiques de l'antigène MSP-3 de <i>Plasmodium falciparum</i>. L'invention concerne, notamment, un anticorps humain de recombinaison spécifique de l'antigène MSP-3¿194-257?. L'invention concerne enfin un acide nucléique codant pour ces anticorps et les utilisations desdits anticorps en particulier dans le traitement ou la prophylaxie de la malaria.
Druilhe Pierre
Dziegiel Morten Steen Hanefeld
Lundquist Rasmus
Nielsen Leif Kofoed
Institut Pasteur
Ram Biotech Aps
Robic
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