Recombinant anti-vla4 antibody molecules

Details Recombinant anti-vla4 antibody molecules Recombinant anti-vla4 antibody molecules

C - Chemistry, Metallurgy

12

N

C12N 15/13 (2006.01) A61K 39/395 (2006.01) A61K 49/00 (2006.01) A61K 51/10 (2006.01) C07K 16/28 (2006.01) C07K 16/46 (2006.01) C12N 5/10 (2006.01) C12N 15/62 (2006.01) G01N 33/564 (2006.01) G01N 33/577 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2153692

The present invention discloses recombinant anti-VLA4 antibody molecules, including humanized recombinant anti-VLA4 antibody molecules. These antibodies are useful in the treatment of specific and non- specific inflammation, including asthma and inflammatory bowel disease. In addition, the humanized recombinant anti-VLA4 antibodies disclosed can be useful in methods of diagnosing and localizing sites of inflammation.

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