C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/13 (2006.01) C07K 16/10 (2006.01) C07K 16/46 (2006.01) G01N 33/531 (2006.01) G01N 33/564 (2006.01) G01N 33/576 (2006.01)
Patent
CA 2670423
Recombinant antibodies, including chimeric antibodies, specific for hepatitis C (HCV) antigenic proteins are provided. The recombinant antibodies specifically bind to diagnostically relevant regions of HCV proteins and are thus suitable for use, for example, as diagnostic reagents for the detection of HCV, and/or as standardization reagents or positive control reagents in assays for the detection of HCV. The recombinant antibodies can also be used in the treatment or prevention of a HCV infection.
L'invention concerne des anticorps recombinants, notamment des anticorps chimériques, spécifiques des protéines antigéniques de l'hépatite C (VHC). Les anticorps recombinants se lient spécifiquement à des régions pertinentes du point de vue du diagnostic des protéines de VHC et conviennent donc à une utilisation, par exemple, comme réactifs de diagnostic pour la détection du VHC, et/ou comme réactifs d'étalonnage ou réactifs témoins positifs dans des tests de détection du VHC. Les anticorps recombinants peuvent également être utilisés dans le traitement ou la prévention d'une infection par le VHC.
Gutierrez Robin A.
Hawksworth David J.
Pinkus Mary S.
Scheffel James W.
Tu Bailin
Abbott Laboratories
Gowling Lafleur Henderson Llp
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