Recombinant aprotinin variants genetically engineered...

C - Chemistry – Metallurgy – 12 – N

Patent

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167/103.05, 530/

C12N 15/15 (2006.01) A61K 38/57 (2006.01) C07K 14/81 (2006.01) C12P 21/02 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2025070

An aprotinin with a deletion of the amino acid proline in position 2 or an addition of alanine-(-2)- glutamine-(-1). Such aprotinin is useful as an active ingredient in medicaments.

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