C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 7/04 (2006.01) A61K 39/12 (2006.01) C07K 14/08 (2006.01) C12N 15/40 (2006.01)
Patent
CA 2396454
The present invention relates to live PRRS viruses which are attenuated by amino acid mutations in a specific site of the viral protein coded by the open reading frame (ORF) selected from the group of ORF 1a, ORF 1b and/or ORF 2. The invention also pertains to nucleotide sequences coding said viruses, methods of generating such viruses and their use for the preparation of a pharmaceutical composition for the prophylaxis and treatment of PRRS infections.
La présente invention concerne des virus SDRP (syndrome dysgénésique respiratoire porcin) actifs, atténués selon l'invention par des mutations d'acides aminés dans un site spécifique de la protéine virale codée par le cadre de lecture ouvert (ORF) sélectionné dans le groupe contenant ORF 1a, ORF 1b et/ou ORF 2. L'invention concerne également des séquences nucléotidiques codant lesdits virus, des procédés de fabrication de tels virus et leur utilisation dans la préparation d'une composition pharmaceutique destinée à la prophylaxie et au traitement d'infections SDRP.
Elbers Knut
Pesch Stefan
Rengbers Heike
Boehringer Ingelheim Vetmedica Gmbh
Fetherstonhaugh & Co.
LandOfFree
Recombinant attenuation of prrsv does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Recombinant attenuation of prrsv, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant attenuation of prrsv will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1676575