Recombinant b. pseudomallei adhesin protein and methods and...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/31 (2006.01) A61K 39/02 (2006.01) C07K 14/195 (2006.01) C07K 16/12 (2006.01) C12Q 1/02 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2674028

Isolated and/or recombinant adhesin polypeptides from B. pseudomallei are provided, which are used as vaccines. Genetic constructs comprising nucleic acid sequences encoding such polypeptides are also provided. Vectors comprising such constructs have been prepared and used for transforming host cells for producing the polypeptides of the invention. Antibodies to such polypeptides are also provided. Such antibodies can be used to detect the presence of B. pseudomallei or B. mallei.

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