C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/21 (2006.01) A61K 35/74 (2006.01) A61K 39/00 (2006.01) A61P 35/00 (2006.01) C07K 14/245 (2006.01) C12N 15/31 (2006.01) C12N 15/63 (2006.01)
Patent
CA 2714276
The invention relates to a recombinant bacterium with E. coli hemolysin secretion system and increased expression and/or increased secretion of full length or partial H1yA. Also disclosed are a process of manufacturing thereof and uses of such bacterium as a medicament.
L'invention porte sur une bactérie recombinante avec un système de sécrétion d'hémolysine d'E. coli et une expression accrue et/ou une sécrétion accrue de HlyA de pleine longueur ou partielle. L'invention porte également sur un procédé de fabrication de cette bactérie et sur ses utilisations comme médicament.
Fensterle Joachim
Gentschev Ivaylo
Goebel Werner
Hotz Christian
Rapp Ulf R.
Aeterna Zentaris Gmbh
Marks & Clerk
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