C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
530/7.04, 195/1.
C12N 15/86 (2006.01) C07K 7/04 (2006.01) C12N 7/01 (2006.01)
Patent
CA 1325610
ABSTRACT The present invention is directed to recombinant baculoviruses which encode fusion polyhedron proteins capable of forming occlusion bodies containing foreign peptides. The recombinant baculoviruses of the invention are formed by insertion into or replacement of regions of the polyhedrin gene that are not essential for occlusion body formation, with foreign DNA fragments by recombinant DNA techniques. The recombinant occlusion bodies produced in accordance with the present invention have uses in vaccine formulations, immunoassays, immobilized enzyme reactions, as biological insecticides, and as expression vectors.
560508
Fraser Malcolm J.
Ploplis Victoria A.
Rosen Elliot D.
American Biogenetic Sciences Inc.
Fraser Malcolm J.
Osler Hoskin & Harcourt Llp
Ploplis Victoria A.
Rosen Elliot D.
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