C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 1/21 (2006.01) A61K 35/74 (2006.01) A61P 35/00 (2006.01) C07K 14/47 (2006.01) C07K 14/55 (2006.01) C12N 15/74 (2006.01) C12N 15/76 (2006.01)
Patent
CA 2424004
The present invention relates to recombinant mycobacteria, particularly recombinant M. bovis, BCG, engineered to express a MUCI polypeptide and human interleukin-2 for use in cancer immunotherapy.
Cette invention concerne des mycobacteria de recombinaison, notamment, M. bovis, B.C.G., obtenues par génie génétique aux fins de l'expression d'un polypeptide MUC1 ainsi que de l'interleukine 2, à utiliser en immunothérapie anticancéreuse.
Chang Helena R.
Chung Maureen A.
O'donnell Michael A.
Sharma Surendra
Beth Israel Deaconess Medical Center
Chang Helena R.
Chung Maureen A.
Gowling Lafleur Henderson Llp
O'donnell Michael A.
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