Recombinant .beta.-cell and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 5/10 (2006.01) A61K 9/66 (2006.01) A61K 35/39 (2006.01) C07K 14/62 (2006.01) C12N 15/85 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2217652

The present invention provides a recombinant, glucose-regulated insulin producing beta cell whose proliferation is controlled by tetracycline or a derivative thereof. The present invention also provides a method for treating a subject with diabetes using the recombinant beta cell of the present invention.

Cellule bêta de recombinaison produisant de l'insuline en fonction du glucose, la prolifération de ses cellules étant contrôlée par la tétracycline ou l'un de ses dérivés. L'invention porte également sur une méthode de traitement d'un patient atteint de diabète en recourant aux cellules bêta de recombinaison susvisées.

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