C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/52 (2006.01) A61K 38/53 (2006.01) C12N 9/00 (2006.01) C12Q 1/25 (2006.01) G01N 33/573 (2006.01)
Patent
CA 2494268
A peptide comprising an Acetyl CoA carboxylase (ACCase) having a deleted biotin binding domain, having a deleted carboxy transferase domain, and having a functional biotin carboxylase (BC) domain is described. A nucleic acid that encodes the peptide described above and a recombinant host cell that contains the nucleic acid and expresses the encoded peptide is also described. A method of identifying Acetyl CoA carboxylase inhibitors, fungicides, and herbicides is also described herein.
L'invention concerne un peptide comprenant une acétyl CoA carboxylase (ACCase) possédant un domaine de fixation de la biotine délété, possédant un domaine carboxy transférase délété et un domaine biotine carboxylase (BC) fonctionnel. Un acide nucléique codant pour le peptide susmentionné et une cellule hôte de recombinaison contenant l'acide nucléique et exprimant le peptide codé sont également décrits. L'invention porte également sur une méthode d'identification d'inhibiteurs de l'acétyl CoA carboxylase, sur des fongicides et sur des herbicides.
Elich Tedd D.
Volrath Sandra L.
Weatherly Stephanie C.
Cropsolution Inc.
Sim & Mcburney
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