C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/55 (2006.01) C12N 9/22 (2006.01) C12N 9/88 (2006.01) C12N 15/09 (2006.01) C12N 15/81 (2006.01) C12P 19/34 (2006.01)
Patent
CA 2453948
A method is provided for the production of a bovine pancreatic protein with a specific desoxyribonuclease activity of at least 6,000 units per mg of protein. Methylotroghic yeast is used as a heterologous host organism. The bovine pancreatic protein is secreted into the growth medium from which it is purified.
Divulgation d'une méthode de production d'une protéine pancréatique bovine ayant une activité spécifique de la désoxyribonucléase d'au moins 6000 unités par mg de protéine. De la levure méthylotrophique est utilisée comme organisme hôte hétérologue. La protéine pancréatique bovine est sécrétée dans le milieu de croissance duquel elle est purifiée.
Mueller Rainer
Ronning Stephanie
Schoen Helmut
Suppmann Bernhard
Thalhofer Johann-Peter
F.hoffmann-La Roche Ag
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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