Recombinant canine adenovirus (cav) containing exogenous dna

C - Chemistry – Metallurgy – 12 – N

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Details

C12N 15/861 (2006.01) C12N 5/10 (2006.01) C12N 15/85 (2006.01)

Patent

CA 2569241

Disclosed and claimed are recombinant adenoviruses, methods of making them, uses for them (including in immunological, immunogenic, vaccine or therapeutic compositions, or, as a vector for cloning, replicating or expressing DNA and methods of using the compositions and vector), expression products from them, and uses for the expression products. More particularly, disclosed and claimed are recombinant canine adenoviruses (CAV) and methods of making them, uses for them, expression products from them, and uses for the expression products, including recombinant CAV2 viruses. Additionally, disclosed and claimed are truncated promoters, expression cassettes containing the promoters, and recombinant viruses and plasmids containing the promoters or expression cassettes.

Sont divulgués et revendiqués des adénovirus recombinants, des techniques pour les produire, des utilisations de ceux-ci (y compris des compositions immunologiques, des compositions immunogènes, des vaccins ou des compositions à visée thérapeutique, ou, comme vecteur pour le clonage, la réplication ou l'expression d'ADN et des techniques pour utiliser les compositions et le vecteur), des produits d'expression de ceux-ci, et des usages des produits d'expression. Plus particulièrement, sont divulgués et revendiqués des adénovirus recombinants d'origine canine (CAV) et des techniques de production de ceux-ci, des utilisations de ceux-ci, des produits d'expression de ceux-ci et des usages des produits d'expression, y compris des virus recombinants CAV2. En outre, sont divulgués et revendiqués des promoteurs tronqués, des cassettes d'expression contenant les promoteurs, et des virus et des plasmides recombinants contenant les promoteurs ou les cassettes d'expression.

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