Recombinant chimeric proteins and methods of use thereof

Details Recombinant chimeric proteins and methods of use thereof Recombinant chimeric proteins and methods of use thereof

C - Chemistry, Metallurgy

12

N

C12N 15/62 (2006.01) A61K 38/16 (2006.01) A61K 38/18 (2006.01) A61K 47/48 (2006.01) C07K 14/495 (2006.01) C07K 14/78 (2006.01) C07K 19/00 (2006.01) C12N 15/63 (2006.01)

Patent

CA 2712304

A chimeric DNA construct comprising a domain derived from a DNA sequence encoding a cellular regulatory factor and a domain derived from a DNA sequence encoding an extracellular matrix protein, wherein said cellular regulatory factor is TGF-.beta. or a TGF-.beta. fragment.

Divulgation d'une construction chimère d'ADN comprenant un domaine dérivé d'une séquence d'ADN codant un facteur de régulation cellulaire et un domaine d'une séquence d'ADN codant une protéine matrice extracellulaire, ledit facteur de régulation cellulaire étant un TGF-bêta ou un fragment de TGF-bêta.

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