Recombinant chimeric vaccine

A - Human Necessities – 61 – K

Patent

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A61K 31/70 (2006.01) A61K 39/12 (2006.01) C07K 14/07 (2006.01) C07K 14/52 (2006.01) C07K 14/525 (2006.01) C07K 14/57 (2006.01) C12N 15/62 (2006.01) C12N 15/85 (2006.01) C12N 15/863 (2006.01) A61K 38/00 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1339346

A recombinant vaccine comprises a vaccine vector which incorporates a first nucleotide sequence capable of being expressed as all or a part of an antigenic polypeptide, together with a second nucleotide sequence capable of being expressed as all or a part of a lymphokine effective in enhancing the immune response to the antigenic polypeptide. The vaccine vectors include poxvirus, herpes virus or adenovirus, and the lymphokine may be an interleukin or gamma-interferon. The vaccine vector may express an antigenic polypeptide which is foreign to the host vector.

543498

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