Recombinant collagenase type i from clostridium histolyticum...

C - Chemistry – Metallurgy – 12 – N

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C12N 9/52 (2006.01) A61K 38/46 (2006.01) C07K 14/33 (2006.01) C12N 15/57 (2006.01) C12P 21/02 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2272244

A polypeptide having the properties of a Class I Clostridium histolyticum collagenase (CHC I) and the amino acid sequence SEQ ID NO:2, the N terminal of which has been optionally extended in one or more amino acids of the sequence SEQ ID NO:3, is advantageously adequate for isolating cells in tissues from mammals and human tissues.

Un polypeptide ayant les propriétés d'une collagénase classe I du Clostridium histolyticum (CHC I) et de la séquence aminoacide SEQ ID NO:2, prolongée éventuellement en N terminal d'un ou plusieurs aminoacides de la séquence SEQ ID NO:3, est avantageusement approprié pour l'isolation de cellules à partir de tissus de mammifères et de tissus humains.

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