Recombinant diphtheria toxin fragments

C - Chemistry – Metallurgy – 12 – N

Patent

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195/1.2, 195/1.2

C12N 15/70 (2006.01) A61K 39/44 (2006.01) A61K 47/48 (2006.01) C07K 7/08 (2006.01) C07K 14/34 (2006.01) C07K 14/415 (2006.01) C07K 16/30 (2006.01) C07K 17/06 (2006.01) C12N 1/21 (2006.01) C12N 15/11 (2006.01) C12N 15/31 (2006.01) C12N 15/52 (2006.01) C12N 15/62 (2006.01) C12N 15/69 (2006.01) A61K 38/00 (2006.01)

Patent

CA 1327329

Abstract of the Disclosure Recombinant vectors which are effective in expressing DNA sequences encoding specific fragments of diphtheria toxins at high levels in recombinant host cells are disclosed. Both a fragment consisting of the enzymatically active A chain of diphtheria toxin and a fragment consisting of both the A portion and a D portion partial sequence are constructed by use of this recombinant vector.

472560

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