C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
195/96, 195/1.14
C12N 15/54 (2006.01) C12N 1/21 (2006.01) C12N 5/10 (2006.01) C12N 9/10 (2006.01) C12P 35/00 (2006.01) C12P 37/00 (2006.01)
Patent
CA 2026262
X-7930 Abstract The present invention provides DNA compounds that encode isopenicillin N:acylCoA acyltransferase activity of Aspergillus nidulans. The compounds can be used to construct recombinant DNA expression vectors for a wide variety of host cells, including E. coli, Penicillium, and Aspergillus. The invention also provides methods for producing cephalosporins in penicillin N-producing fungi.
Miller James R.
Skatrud Paul L.
Tobin Matthew B.
Eli Lilly And Company
Gowling Lafleur Henderson Llp
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