C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C07K 14/165 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01)
Patent
CA 2259964
The present invention relates to a recombinant DNA vector comprising a cDNA copy of at least a part of the genome of equine arteritis virus. The recombinant DNA vector according to the present invention is stable in a vector host cell and yields, after transcription, infectious RNA. Due to the invention the genetic engineering of the virus is very much simplified and it may be used for, among other things, the preparation of pharmaceutical compositions. Licensing possible.
L'invention a pour objet un vecteur d'ADN recombiné contenant une copie ANDc d'au moins une partie du génome du virus equine arteritis. Le vecteur d'ADN recombiné conforme à l'invention, stable dans une cellule hôte du vecteur, produit, après transcription, un ARN infectieux. Grâce à l'invention, l'obtention par génie génétique du virus est de beaucoup simplifiée. Ledit virus peut être utilisé, notamment, pour la préparation de compositions pharmaceutiques. Obtention de licence possible.
Bredenbeek Petrus Johannes
Den Boon Johan Arie
Snijder Eric John
Spaan Wilhelmus Josephus Maria
Van Dinten Leonie Christina
Moffat & Co.
Rijksuniversiteit Leiden
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