Recombinant dna virus and method for preparation thereof

C - Chemistry – Metallurgy – 12 – N

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C12N 15/86 (2006.01) C12N 7/01 (2006.01) C12N 15/861 (2006.01)

Patent

CA 2171368

A recombinant DNA virus for transfecting an animal cell and bearing a foreign gene and a promoter capable of regulating expression of the foreign gene is completely deleted of the function of E2A gene. The recombinant DNA virus can thus stably transduce the foreign gene into various animal cells, which leads to continuous expression of the foreign gene in the animal cells. The continuous expression of the foreign gene can provide an effective treatment of hereditary disease.

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