Recombinant expression vectors capable of expressing...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/62 (2006.01) A61K 39/015 (2006.01) A61K 39/112 (2006.01) C07K 14/11 (2006.01) C07K 14/24 (2006.01) C07K 14/445 (2006.01) C07K 19/00 (2006.01) C12N 1/21 (2006.01) C12N 15/30 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2050876

1 HOE 90/B 029 - Ma 846 Recombinant expression vectors capable of expressing immunogenic malarial antigens on the surface of Sal- monella vaccine strains ABSTRACT Recombinant expression vectors are described which can be used for the expression of the malarial antigens HRPII or SERP or of parts thereof on the surface of gram-negative bacteria being capable of inducing a humoral immune response in mammals. Furthermore, corresponding Salmonella-based vaccines are described.

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