Recombinant factor viii having increased stability

Details Recombinant factor viii having increased stability Recombinant factor viii having increased stability

C - Chemistry, Metallurgy

07

K

C07K 14/755 (2006.01) A61K 38/37 (2006.01) A61P 7/04 (2006.01) C12N 15/12 (2006.01) C12P 21/02 (2006.01)

Patent

CA 2703948

The present invention relates to a recombinant factor VIII that includes one or more mutations that result in enhanced stability of both factor VIII and factor VIIIa. Methods of making and using the recombinant factor VIII, and pharmaceutical compositions containing the same are also disclosed. The present invention further relates to an isolated nucleic acid molecule that encodes the recombinant factor VIII, as well as DNA expression systems and host cells containing the isolated nucleic acid molecule.

La présente invention porte sur un facteur VIII recombinant qui comprend une ou plusieurs mutations qui conduisent à une stabilité accrue à la fois du facteur VIII et du facteur VIIIa. L'invention porte également sur des procédés de fabrication et d'utilisation du facteur VIII recombinant et sur des compositions pharmaceutiques contenant ceux-ci. La présente invention porte également sur une molécule d'acide nucléique isolée qui code pour le facteur VIII recombinant, ainsi que sur des systèmes d'expression d'ADN et des cellules hôtes contenant la molécule d'acide nucléique isolée.

Affiliated with

Also associated with

Rating

Recombinant factor viii having increased stability does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant factor viii having increased stability, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant factor viii having increased stability will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2087176