Recombinant fowlpox viruses and uses thereof

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 7/01 (2006.01) A61K 31/70 (2006.01) A61K 39/17 (2006.01) A61K 39/275 (2006.01) A61K 39/295 (2006.01) A61K 48/00 (2006.01) C12N 15/19 (2006.01) C12N 15/86 (2006.01) C12N 15/863 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2223591

This invention provides a recombinant fowlpox virus comprising a foreign DNA sequence inserted into the fowlpox virus genomic DNA, wherein the foreign DNA sequence is inserted within a non-essential region of the fowlpox virus genomic DNA and is capable of being expressed in a fowlpox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.

Virus de variole aviaire recombiné comportant une séquence d'ADN étrangère insérée dans l'ADN génomique du virus du variole aviaire, la séquence d'ADN étrangère étant insérée au sein d'une région non essentielle de l'ADN génomique du virus de variole aviaire, et pouvant être exprimée dans une cellule hôte infectée par le virus de variole aviaire. L'invention concerne également des vecteurs d'homologie, des vaccins et des méthodes d'immunisation.

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