Recombinant fusion molecules

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A01H 5/00 (2006.01) A61K 39/21 (2006.01) C07K 14/155 (2006.01) C07K 14/16 (2006.01) C07K 16/10 (2006.01) C12N 15/62 (2006.01) C12N 15/82 (2006.01) C12P 21/02 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2388955

This invention relates to a method for increasing the production of a protein in a cell and more particular by the production in a plant cell. This invention also relates to recombinant immune fusion complexes and more particularly to their expression in plants. Specific constructs comprising gp 120 fused to the heavy chain constant region of an antibody or part thereof are disclosed as well as the use of such constructs in generating an immune response.

Cette invention a trait à une méthode permettant d'augmenter la production d'une protéine dans une cellule et, plus particulièrement, cette production dans une cellule végétale. Elle porte également sur des complexes hybrides immuns de recombinaison et, notamment, sur leur expression dans des végétaux. L'invention concerne, de surcroît, des produits de recombinaison spécifiques renfermant le virus gp 120 fusionné à la région constante de la chaîne lourde d'un anticorps ou d'une partie de celui-ci, ainsi que l'usage qui est fait de ces produits de recombinaison pour déclencher une réaction immunitaire.

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