Recombinant herpes simplex gb-gd vaccine

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/38 (2006.01) A61K 39/245 (2006.01) C07K 14/035 (2006.01) C12N 1/19 (2006.01) C12N 5/10 (2006.01) C12N 15/81 (2006.01) A61K 39/00 (2006.01)

Patent

CA 1337181

Vaccines and methods for production of vaccines effective against Herpes Simplex Virus (HSV) are provided employing recombinant HSV glycoproteins B and D and immunogenically active fragments thereof. The following E. coli HB101 strains were deposited at the A.T.C.C., where the plasmid indicates the plasmid employed to transform the strain: pHS203; pHS112; pHS114; pHS127A and pHS206 were deposited on April 4, 1984, and assigned Accession Nos. 39649-39653, respectively; pYHS109 and pYHS118 were deposited on July 11, 1984, and given Accession Nos. 39762 and 39763 respectively.

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