C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/86 (2006.01) A61K 31/70 (2006.01) A61K 48/00 (2006.01) C12N 5/10 (2006.01) C12N 7/01 (2006.01) C12P 21/02 (2006.01)
Patent
CA 2234604
Methods for treatment, processes for preparing, and compositions for delivering selected nucleic acid sequences to cells, primarily of the treatment of neurological disorders and exploring neurological functions, are disclosed. In particular, the invention provides recombinant Herpesvirus vectors with a high rate of expression of selected nucleic acid sequences and/or a low cytopathicity and its associated methods and processes.
Méthodes de traitement, procédés d'élaboration et compositions destinés à l'administration de certaines séquences d'acide nucléique à des cellules, essentiellement pour le traitement des désordres neurologiques et l'exploration des fonctions neurologiques. L'invention porte en particulier sur des vecteurs d'herpesvirus de recombinaison présentant un taux élevé d'expression de séquences d'acide nucléique et/ou une faible cytopathicité, sur les méthodes et sur les procédés associés.
Cynader Max
Tufaro Francis
Gowling Lafleur Henderson Llp
The University Of British Columbia
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