Recombinant herpes viruses, a vaccine based on these...

C - Chemistry – Metallurgy – 12 – N

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C12N 7/01 (2006.01) A61K 39/255 (2006.01) C07K 14/055 (2006.01) C07K 14/125 (2006.01) C12N 9/12 (2006.01) C12N 15/38 (2006.01) C12N 15/869 (2006.01) A61K 39/00 (2006.01)

Patent

CA 2050850

26361-74 New recombinant herpes viruses, a vaccine based on these recombinants, their preparation process, genes, vectors and plasmids used in this process. Abstract The invention concerns the sequence of the unique short region Us of Marek's disease virus coding for the kinase protein. It also concerns the recombinant herpes viruses in which a hetero- logous gene has been inserted in the homologous region of the gene coding for the kinase protein and, in particular, the Marek recom- binant viruses expressing a gene of an avian pathogenic agent which could possibly be a gene of another serotype of the Marek viruses. It also concerns a process for the preparation of these recombinants as well as the vaccines obtained.

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