Recombinant hosts

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

CPC

195/1.29, 195/1.

IPC codes

C12N 15/71 (2006.01) C07K 14/52 (2006.01) C12N 1/20 (2006.01) C12N 15/11 (2006.01)

Type

Patent

Patent number

CA 1338664

Description

A genomically modified host is provided wherein a regulatable promoter is more effectively induced due to inefficient production of an aporepressor-activator. The same regulatable promoter is then used on recombinant expression vectors transformed into the host for recombinant protein production. This results in higher levels of expression of the desired recombinantly produced protein. A specific aspect of the invention is shown in Fig. 1.

Application Number

504577

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