Recombinant hsv-1 and live viral vaccines

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

C12N 15/869 (2006.01) A61K 35/76 (2006.01) A61K 39/245 (2006.01)

Patent

CA 2381056

The invention concerns a recombinant herpes simplex virus which genome has been altered by mutations or deletions in the unique small (US) 8 and 12 genes. The invention further concerns vaccines comprising said recombinant herpes simplex virus.

L'invention concerne un herpès simplex virus recombinant dont le génome a été altéré par des mutations ou des délétions dans les gènes uniques de petite taille 8 et 12. L'invention concerne également des vaccins comprenant ledit herpès simplex virus recombinant.

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