Recombinant hybrid immunogloblin molecules an method of use

C - Chemistry – Metallurgy – 12 – N

Patent

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Details

530/15.06, 195/1

C12N 15/62 (2006.01) A61K 38/49 (2006.01) A61K 39/395 (2006.01) A61K 47/48 (2006.01) A61K 51/10 (2006.01) C07K 16/36 (2006.01) C12N 9/72 (2006.01) C12N 15/13 (2006.01) C12N 15/58 (2006.01) G01N 33/577 (2006.01)

Patent

CA 1339546

This invention relates to a recombinant hybrid immunoglobulin molecule having an antigen binding site specific for fibrin linked to a second protein comprising the active portion of a plasminogen activator, single-chain urokinase. The invention is also directed to the cloning and production of these novel hybrid immunoglobulin molecules. This invention further relates to a method of using these recombinant hybrid immunoglobulin molecules in immunodiagnostic and immunotherapeutic processes.

608894

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