Recombinant igf expression systems

Details Recombinant igf expression systems Recombinant igf expression systems

C - Chemistry, Metallurgy

07

K

C07K 14/65 (2006.01) C07K 14/00 (2006.01)

Patent

CA 2529282

The present invention provides nucleic acid sequences, expression systems, host cells, polypeptides and methods of producing mature insulin-like growth factor (IGF) using a fusion construct which yields high levels of fusion proteins that are easily processed to provide IGF with a proper N-terminus.

La présente invention concerne des séquences nucléotidiques, des systèmes d'expression, des cellules hôtes, des polypeptides et des procédés de production de facteur de croissance insulinoïde (IGF) mature à l'aide d'une construction de fusion laquelle permet d'obtenir des niveaux élevés de protéines de fusion qui sont traitées facilement pour produire un IGF ayant une partie N-terminale correcte.

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