Recombinant il-5 antagonists useful in treatment of il-5...

C - Chemistry – Metallurgy – 12 – N

Patent

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C12N 15/13 (2006.01) A61K 39/395 (2006.01) C07K 14/54 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/46 (2006.01) C12N 5/18 (2006.01) G01N 33/564 (2006.01) G01N 33/577 (2006.01) G01N 33/68 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2208503

Chimeric, humanized and other IL-5 mAbs, derived from high affinity neutralizing mAbs, pharmaceutical compositions containing same, methods of treatment and diagnostics are provided.

L'invention porte sur des anticorps monoclonaux (mAbs) chimériques humanisés anti-interleukine-5 (IL-5) et sur d'autres dérivés de mAbs neutralisants, à haute affinité, sur des préparations pharmaceutiques les contenant, et sur des méthodes de traitement et de diagnostic associées.

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