C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 16/24 (2006.01) A61K 39/395 (2006.01) A61K 47/42 (2006.01) A61K 47/48 (2006.01) A61P 29/00 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 37/00 (2006.01) G01N 33/53 (2006.01)
Patent
CA 2521826
The present invention provides novel antibodies that immunospecifically bind to an IL-9 polypeptide and compositions comprising said antibodies. The present invention also provides methods and compositions preventing, treating, managing, and/or ameliorating diseases and disorders associated with aberrant expression and/or activity of IL 9 or IL-9 receptor or subunits thereof, autoimmune diseases, inflammatory diseases, proliferative diseases, and infections comprising administration of one or more antibodies thereof that immunospecifically bind to an IL-9 polypeptide. The invention also encompasses methods and compositions for diagnosing, monitoring, and prognosing these disorders. The present invention further relates to articles of manufacture and kits comprising antibodies that immunospecifically bind to an IL-9 polypeptide.
La présente invention a trait à de nouveaux anticorps de liaison immunospécifique à un polypeptide IL-9 et des compositions comprenant lesdits anticorps. La présente invention a également trait à des procédés et des compositions pour la prévention, le traitement, le contrôle, et/ou l'amélioration de maladies et de troubles associés à l'expression et/ou l'activité aberrante de IL-9 ou de récepteur de IL-9 ou des sous-unités de ceux-ci, de maladies auto-immunes, de maladies inflammatoires, de maladies proliférantes, et d'infections comprenant l'administration d'un ou de plusieurs anticorps de l'invention qui sont de liaison immunospécifique à un polypeptide IL-9. L'invention a trait en outre à des procédés et des compositions pour le diagnostic, le suivi, et le pronostic de ces troubles. Enfin, l'invention a trait à des articles de fabrication et des trousses comportant des anticorps de liaison immunospécifique à un polypeptide IL-9.
Davies Julian
Reed Jennifer L.
Tang Ying
Watkins Jeffry D.
Wu Herren
Medimmune Inc.
Osler Hoskin & Harcourt Llp
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