Recombinant influenza virus strains for vaccines

Details Recombinant influenza virus strains for vaccines Recombinant influenza virus strains for vaccines

A - Human Necessities

61

K

167/132

A61K 39/145 (2006.01)

Patent

CA 1044138

ABSTRACT A recombinant influenza virus strain derived from (a) an over-attenuated influenza A strain which has been passaged solely in chicken egg cultures, manifests a relatively high yield of virus in such cultures and has an increased capacity for plaque formation of calf kidney cells and (b) a virulent influenza A strain which mani- fests a relatively low culture yield of virus and is sub- stantially free from contaminating mammalian viruses; a method of manufacturing the recombinant strain and a vaccine incorporating it. The virulent strain is preferably one fairly recently isolated at the time of manufacture of the vaccine. The over-attenuated strain should have sufficient antigenic distinction between it and the virulent strain and have a proven safety record.

214815

Affiliated with

Also associated with

Rating

Recombinant influenza virus strains for vaccines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Recombinant influenza virus strains for vaccines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Recombinant influenza virus strains for vaccines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-66024