Recombinant marek's disease virus, process for preparing the...

C - Chemistry – Metallurgy – 12 – N

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167/130, 195/1.2

C12N 7/01 (2006.01) A61K 39/255 (2006.01) C07K 14/055 (2006.01) C12N 15/86 (2006.01) C12N 15/869 (2006.01)

Patent

CA 1339774

A recombinant Marek's disease virus which comprises a Marek's disease virus genom and a DNA fragment incorporated therein, said DNA fragment being constructed by incorporating a promoter derived from an animal cell or an animal virus and a structural gene coding for an exogenous protein into a gene fragment derived from a Marek's disease virus, a process for preparing the same which comprises preparing a gene fragment wherein a structural gene coding for an exogenous gene is linked to the downstream of a promoter derived from an animal cell or an animal virus, incorporating said gene fragment into a BamHI - H fragment of a gene of a Marek's disease virus type I, and incorporating said fragment into a Marek's disease virus type I genome, and a multivalent live vaccine for birds comprising the same.

610801

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