Recombinant methods and materials

C - Chemistry – Metallurgy – 12 – N

Patent

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195/1.15, 195/1.

C12N 15/00 (2006.01) C12N 15/63 (2006.01) C12N 15/85 (2006.01) C12N 15/90 (2006.01)

Patent

CA 1214408

ABSTRACT Specific DNA sequence insertions, deletions and substitutions (i.e., combinations of sequence deletion and insertion) in eukaryotic cell or viral genomes are stably effected through use of selectable DNA sequences comprising a herpesvirus thymidine kinase (tk) gene.

411481

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