Recombinant modified thermostable nad-dependent...

C - Chemistry – Metallurgy – 12 – N

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C12N 15/53 (2006.01) C12N 9/00 (2006.01) C12N 9/04 (2006.01) C12N 15/52 (2006.01)

Patent

CA 2047707

2047707 9010702 PCTABS00002 A recombinant thermophilic NAD-dependent dehydrogenase having a hydrophobic amino acid at position 104 and/or 102. The enzymes are effective in catalysing the dehydrogenation of homologues of pyruvic acid of formula CnH2n+1COCOOH, wherein n is > 1, to homologues of lactic acid of formula CHnH2n+1CHOHCOOH, wherein n is > 1.

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